Pharmaceutical Form
• Compressed medical gas (for medicinal use only)

Mixtures
50% Nitrous Oxide/50% Oxygen

Uses
Entonox is a very potent analgesic with a very rapid onset of action and rapid elimination from the body. It is widely used by midwives and the ambulance service, it is also the ideal analgesic for short surgical procedures. Examples:

• Child birth
• Acute trauma
• Short term relief in dental work
• Fracture manipulation
• Joint manipulation
• Endoscopy
• Venopuncture
• Wound and burn dressings, wound debridement and suturing

Dosage and Administration
Doses may be self regulated in nearly all cases by the use of a face mask connected through a demand valve to the Entonox cylinder.

Entonox may be administrated by personnel trained in its use (obstetric units, accident units and accident ambulances).

There is no risk of overdose with Entonox in medical use.

Entonox is administered through a face mask. The mask is connected to an Entonox supply through a demand valve system. The valve is operated by the act of inhalation of the patient and closes down when the patient ceases to inhale.

In nearly all cases, Entonox is self-administered, but it may be administered by attending medical personnel. Since pain is usually relieved by a concentration of 25% nitrous oxide, continued inhalation does not occur. However, should inhalation continue, light anæsthesia supervenes and mask drops away as the patient relaxes, or is removed if administration has been by attending personnel.